Demographic, clinical and analytical characteristics of patients.

Data are expressed as mean (standard deviation), median [percentiles 25th–75th] or absolute number (percentage).
ACEI =  angiotensin-converting enzyme inhibitor; ARB =  angiotensin II receptor blocker; BMI =  body mass index; COPD: Chronic obstructive pulmonary disease; eGFR =  estimated glomerular filtration rate; HF, heart failure; hs-cTnT, high-sensitivity circulating troponin T; ST2 =  high-sensitivity soluble ST2; LVEF =  left ventricular ejection fraction; NT-proBNP =  N-terminal pro-brain natriuretic peptide; NYHA =  New York Heart Association. CRT =  cardiac resynchronization therapy; ICD =  implantable cardiac defibrillator.
Ref.  =  Reference.
Loop diuretic dose 1: Furosemide-equivalent dose up to 40 mg/day or Torasemide up to 10 mg/day.
Loop diuretic dose 2: Furosemide-equivalent dose >40 mg/day or Torasemide>10 mg/day.
The logarithmic functions of NTproBNP, hs-cTnT and cystatin C, the quadratic term of the logarithmic function of hs-cTnT, ST2 as ST2/10 and the quadratic term of ST2/10 were used in the Cox models. P value for (ST2/10)2<0.001 in the univariate analysis and 0.006 in the multivariate analysis; P value for log(hs-cTnT)2<0.001 in the univariate analysis and 0.015 in the multivariate analysis.