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Crystal structure of Trk-A complexed with a selective inhibitor CH7057288

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of Trk-A complexed with a selective inhibitor CH7057288 Descriptor: High affinity nerve growth factor receptor, N-tert-butyl-2-[2-[6,6-dimethyl-8-(methylsulfonylamino)-11-oxidanylidene-naphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methyl-pyridine-4-carboxamide Authors: Tanaka, H, Blaesse, M, Augustin, M, Goesser, C. Deposit date: 2016-11-30 Release date: 2017-12-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Selective TRK Inhibitor CH7057288 against TRK Fusion-Driven Cancer. Mol. Cancer Ther., 17, 2018
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2016-11-30
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