The sequence information of BLR, C73, and HM26
收藏科学数据银行2024-08-23 更新2026-04-23 收录
下载链接：
https://www.scidb.cn/detail?dataSetId=b4c8203bddec431eb097b8aaf63b4f57
下载链接
链接失效反馈官方服务：
资源简介：
Unveiling the molecular mechanisms underlying rotavirus replication and pathogenesis had been hampered by the lack of a reverse genetics (RG) system in the past. Since 2017, multiple plasmid-based RG systems for simian, human, and murine-Like rotaviruses have been established. However, none of the described methods have supported the recovery of bovine rotaviruses (BRVs). Here, an optimized plasmid-based RG system for BRV culture-adapted strain (BRV G10P [15] BLR) and clinical isolates (BRV G6P[1] C73, G10P[11] HM26) was established based on a BHK-T7 cell clone stably expressing T7 polymerase.
提供机构：
Jitao Chang; Songkang Qin; Zhigang Jiang; Benjin Liu; Yuxin Han; Harbin Veterinary Research Institute; Yinglin Qi; Debin Yu; Kuanhao Li
创建时间：
2024-08-21
