Hazard Ratios (HR) and 95% Confidence Intervals (CI) for colorectal cancer characterized by CIMP, according to measures of anthropometry in the NLCS after 7.3 years of follow-up.

*models adjusted for age and sex.†models adjusted for age, sex, and additionally for family history of CRC (yes/no), smoking status (never smoker, ex-smoker, current smoker), socioeconomic status (level of education: primary school, junior high school, senior high school, higher vocational school, or university), total energy intake (kcal/day), alcohol intake (0, 0.1–4, 5–14, 15–29, ≥30 g/day), and consumption of red meat, fruit, vegetables, and grains (g/day). Models with anthropometric variables were additionally adjusted for baseline physical activity (based on recreational physical activity for women (low≤30 minutes/day, intermediate = 30–90 minutes/day, high≥90 minutes/day) and occupational physical activity at the longest held job for men (low≤8 kj/minute, intermediate = 8–12 kj/minute, and high≥12 kj/minute).‡Models adjusted for age and sex, and mutually adjusted for other anthropometric variables. Models with BMI and BMI at age 20 were additionally adjusted for trouser/skirt size; the model for BMI change was additionally adjusted for BMI at age 20; the model with trouser/skirt size was additionally adjusted for BMI; the model with height was additionally adjusted for body weight.§P value for test that HR for two tumor subtypes are equal (based on model 3).