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Genome wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress

ChEBI2014-04-30 更新2026-07-21 收录

肿瘤抑制基因

DNA损伤应答

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-56640 数据链接链接失效反馈

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Genome wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress

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2014-04-30

癌症信号传导

DNA损伤应答

Transcriptional profile of RasV12 expressing cells shows an upregulation of RTK signalling genes and a downregulation in genes involved in DNA sintesis and DNA damage response. mRNA expression profile

NIAID Data Ecosystem50

WTX overexpression effect on gastric cell line

癌症分子机制

肿瘤抑制基因

We used microarrays to detail the global gene expression in AGS gastric cancer cells overexpressing WTX, a tumor suppressor frequently inactivated in Wilms tumor. Results provide insight into roles fo

NIAID Data Ecosystem30

Gene expression in Stage 1,2 Normal and Tumor kidney cancer. Homo sapiens

癌症分子机制

肿瘤抑制基因

Although renal cell carcinoma (RCC) is the sixth-leading cause of cancer death, the molecular events leading to disease onset and progression are not well understood. Genomic profiling of clear cell R

NIAID Data Ecosystem10

Additional file 5: Table S5. of Concordance of copy number loss and down-regulation of tumor suppressor genes: a pan-cancer study

癌症基因组数据

肿瘤抑制基因

The CNV frequency of 81 tumor suppress genes (TSGs) with decreased gene expression potentially induced by copy number losses (CNLs) in multiple cancers. (XLSX 12 kb)

DataCite Commons2024-12-12 更新40

Arrest of G(1)-S Progression by the p53-Inducible Gene PC3 Is Rb Dependent and Relies on the Inhibition of Cyclin D1 Transcription

细胞周期调控

肿瘤抑制基因

The p53-inducible gene PC3 (TIS21, BTG2) is endowed with antiproliferative activity. Here we report that expression of PC3 in cycling cells induced accumulation of hypophosphorylated, growth-inhibitor

PubMed Central30

Genome wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress

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