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Crystal structure of CDK2 in complex with inhibitor BS-194

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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Crystal structure of CDK2 in complex with inhibitor BS-194 Descriptor: (2S,3S)-3-{[7-(benzylamino)-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-5-yl]amino}butane-1,2,4-triol, Cell division protein kinase 2 Authors: Hazel, P, Freemont, P.S. Deposit date: 2010-07-01 Release date: 2010-12-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.78 Å) Cite: A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration. J.Med.Chem., 53, 2010
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2010-07-01
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