Change in metabolite concentrations following allogeneic and syngeneic bone marrow transplantation.

Lethally irradiated B6 recipients (Irradiated) were transplanted with 5×106 T-cell depleted bone marrow cells (TCD-BM) and 3×106 CD90+ T-cells from B6 Thy1.1 (Syngeneic) or Balb/C (Allogeneic) donor mice.All units are µmol/L unless otherwise noted and values are expressed as Mean±SD.Statistical Analysis of Microarray with Tukey’s post hoc test was used to determine statistical differences between groups.Different letters denote significant differences among treatment groups (e.g. a versus b).1F. GSH - non-protein bound Free GSH.2GSSG – glutathione disulfide.3GSH/GSSG (mV) – GSH/GSSG redox potential was calculated using the Nernst Equation as described in methods.4T. Homocysteine – Total Homocysteine concentration obtained following plasma reduction with dithiothreitol (DTT).5Cysteine – Total Cysteine concentration obtained following plasma reduction with dithiothreitol (DTT).6FDR- False discovery rate.