The Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer Components.

Data from ProteomeXchange, PXD ID: PXD002113. File: 130514_LA_C_92_SAX8.mzml. Published as part of PLoS Pathog. 2015 Jun 4;11(6):e1004883 . From the Abstract: {{i}} Chlamydia trachomatis is an important human pathogen that replicates inside the infected host cell in a unique vacuole, the inclusion. The formation of this intracellular bacterial niche is essential for productive Chlamydia infections. Despite its importance for Chlamydia biology, a holistic view on the protein composition of the inclusion, including its membrane, is currently missing. Here we describe the host cell-derived proteome of isolated C. trachomatis inclusions by quantitative proteomics. ... {{/i}}