首页/数据集/Retinoic acid and Azakenpoullone treatment in SH-SY5Y/6TR(EU)/pTrex-Dest-30/MYCN cell line in high and low MYCN levels

Retinoic acid and Azakenpoullone treatment in SH-SY5Y/6TR(EU)/pTrex-Dest-30/MYCN cell line in high and low MYCN levels

ChEBI2015-06-30 更新2026-07-12 收录

神经母细胞瘤药物筛选

MYCN基因表达调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-2689 数据链接链接失效反馈

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资源简介：

Retinoic acid and Azakenpoullone treatment in SH-SY5Y/6TR(EU)/pTrex-Dest-30/MYCN cell line in high and low MYCN levels

应用场景：

创建时间：

2015-06-30

组蛋白去乙酰化酶抑制剂

神经母细胞瘤药物筛选

Histone deacetylases (HDACs) are critical in the control of gene expression and dysregulation of their activity has been implicated in a broad range of diseases including cancer, cardiovascular and ne

NIAID Data Ecosystem50

Bulk RNA-sequencing of MYCN-overexpressing chicken retinal cell lines

视网膜母细胞瘤致癌机制

MYCN基因表达调控

Background: MYCN gene is a transcription factor whose amplification and overexpression can lead to tumorigenesis. In retina, MYCN overexpression is related to tumorigenesis of retinoblastoma, a childh

NIAID Data Ecosystem20

RNA-seq in human neuroblastoma SK-N-BE(2)-C cells treated with DMSO, TSA or E6R

神经母细胞瘤药物筛选

转录组学分析

As part of a larger study identifying novel HDAC complex inhibitors, cells were treated with 0.8% DMSO, 1 μM TSA, or 25 μM E6R to investigate changes in gene expression levels. SK-N-BE(2)-C cells were

NIAID Data Ecosystem10

Utilizing Omomyc to Target MYCN-Amplified Diffuse Intrinsic Pontine Gliomas

DIPG治疗

MYCN基因表达调控

Genomic studies have shown that several types of pediatric brain tumors have dysregulation of MYC family members (c-MYC and MYCN). In fact, it has been estimated that about 50% of all human cancers ha

NIAID Data Ecosystem30

Viability of SH-SY5Y neuroblastoma cells treated with ATRA (dose-response) alone or in the presence of AA-signalling inhibitors.

神经母细胞瘤药物筛选

细胞活力剂量反应

*ATRA alone: Viability at 15 µM.SH-SY5Y cells were pre-treated for 2 h with inhibitor (or vehicle control) at the concentrations specified (left column) prior to the addition of ATRA and viability was

Figshare2015-12-02 更新10

Retinoic acid and Azakenpoullone treatment in SH-SY5Y/6TR(EU)/pTrex-Dest-30/MYCN cell line in high and low MYCN levels

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