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T cell-specific RIPK1 ablation results in villus atrophy of the duodenum in mice

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE263990
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RIPK1 is required in T cells with a history of CD4-expression to maintain intestinal homeostasis. We show that the pathology in the upper intestine is a result of conventional T cell apoptosis in absence of the RIPK1. Four samples in total: Two intraepithelial lymphocytes (IEL) samples: Ripk1FL/FL and Ripk1ΔCD4; Two lamina propria lymphocytes (LPL) samples: Ripk1FL/FL and Ripk1ΔCD4
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2025-05-02
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