Whole exome sequencing and RNAseq of naturally-occurring colorectal cancer in rhesus macaques

Naturally occurring colorectal cancers (CRC) in rhesus macaques share many features with their human counterparts and emerge at similar life stages as in human patients, but the carcinogenesis and molecular background remain elusive, limiting the value of the model for human disease and cancer therapy. Here we use whole exome and RNAseq for molecular characterization of naturally-occurring colorectal cancer in rhesus macaques.