Expression microarray analysis of HaCaT epidermal keratinocyte treated with AdcaRAS/dnRAS, p53 siRNA, and/or TGF-beta
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE60813
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资源简介：
We demonstrate that activation of Ras and TGF-β pathways strengthens the binding of p63 to its genomic sites and modulates the expression of p63 target genes. Our findings support a model of mutual inhibition between ΔNp63α, DUSP6 and mutant p53 downstream of oncogenic Ras and TGF-β. We used expression microarrays to evaluate the effect of caRAS/dnRAS, p53 siRNA, and/or TGF-beta in HaCaT epidermal keratinocyte.
创建时间：
2019-03-25
