Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor
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Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor Descriptor: 1-(2-azanylethyl)-3-(3,4-dichlorophenyl)-~{N}-(phenylmethyl)pyrazole-4-carboxamide, MYRISTIC ACID, Transcriptional enhancer factor TEF-4 Authors: Sturbaut, M, Allemand, F, Guichou, J.F. Deposit date: 2019-07-02 Release date: 2020-07-22 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors. Eur.J.Med.Chem., 226, 2021
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2019-07-02
