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A Straightforward Synthesis of Enantiopure (1S,2R)-Ephenamine

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DataCite Commons2021-03-25 更新2024-07-28 收录
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https://scielo.figshare.com/articles/dataset/A_Straightforward_Synthesis_of_Enantiopure_1S_2R_-Ephenamine/14304065
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资源简介:
An enantioselective six-step synthesis of (1S,2R)-ephenamine starting from readily available chiral amino acid is disclosed presenting 26% overall yield and high optical purity. The use of chiral phenylglycine as starting material was also studied and did not present satisfactory results due to a very sensitive a-carbonyl/benzylic stereogenic center that, in our hands, led to racemization.
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SciELO journals
创建时间:
2021-03-25
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