Crystal structure of human T1061E PI3Kalpha in complex with its regulatory subunit and the inhibitor GDC-0077 (Inavolisib)
收藏Protein Data Bank Japan2026-03-04 更新2026-03-28 收录
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Crystal structure of human T1061E PI3Kalpha in complex with its regulatory subunit and the inhibitor GDC-0077 (Inavolisib) Descriptor: (2R)-2-[[2-[(4S)-4-[bis(fluoranyl)methyl]-2-oxidanylidene-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Goncalves, M, Johnson, J.L, Roewer, K.M. Deposit date: 2022-08-02 Release date: 2023-12-13 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.818 Å) Cite: Epinephrine inhibits PI3K alpha via the Hippo kinases. Cell Rep, 42, 2023
创建时间：
2022-08-02
