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Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells [PRO-seq washout]

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NIAID Data Ecosystem2026-03-13 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP356661
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资源简介:
We acutely depleted the BCL11A protein by using the dTAG PROTAC technology, then performed a drug washout and and assessed its immediate consequences nascent transcription. Overall design: Examination of changes in Nascent transcription that occur imminently upon washout of drug to restore transcription factor BCL11A in two clones.
创建时间:
2022-07-20
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