Submission ID: 477c38fa-a933-46be-baa1-2f0197f77068

Methods: This multi-center, retrospective study analyzed 66 patients with TP53-mutated AML/MDS who underwent allo-HSCT. The study endpoints included overall survival (OS), progression-free survival (PFS), and cumulative incidence of relapse (CIR) and non-relapse mortality (NRM). Subgroup analyses and multivariate models were utilized to assess the impact of genetic profiles and clinical characteristics on outcomes following transplantation.