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In vitro methylation studies in multiple human cell types [HumanMethylation850 array]

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE197723
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An Infinium microarray (Illumina Infinium HumanMethylation850 BeadChip) was used to generate DNA methylation data from human tissue samples. n=317 samples. Different sources of human DNA: skin, basal cell carcinoma, keratinocytes, fibroblasts, endothelial cells, keratinocyte stem cells, induced pluripotent stem cells, HUVEC, HCAEC, neural progenitor. These cells were exposed to different conditions and treatments: CCCP (Mitochondrial oxidative phosphorylation uncoupler), bezafibrate, hTERT immortalization, chronic radiation, rapamycin. Genome annotations of the array can be downloaded from https://support.illumina.com/downloads/infinium_humanmethylation450_product_files.html
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2023-10-26
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