Single cell transcriptome analysis of sham and bilateral renal ischemia-reperfusion injury (IRI)

A rat model of bilateral IRI has been widely used to understand how IRI introduces and progresses the damages on kidney. The aim of this study is to reveal the molecular details of how this bilateral IRI impacts kidney cells. Here, we provide rat single-cell RNA-seq data which is a foundation to understand the IRI related kidney disease. It will support studies to clarify pathophysiology and to develop effective therapy exploiting similar rat renal disease models. Kidney mRNA profiles of 6-week-old sham and IRI rats