Crystal structure of human MAP4K1 with an inhibitor, BAY-405
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Crystal structure of human MAP4K1 with an inhibitor, BAY-405 Descriptor: GLYCEROL, Mitogen-activated protein kinase kinase kinase kinase 1, ~{N}-[3,5-bis(fluoranyl)-4-[[3-[1-(trifluoromethyl)cyclopropyl]-1~{H}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-2,9-dioxa-4-azaspiro[5.5]undec-3-en-3-amine Authors: Schaefer, M. Deposit date: 2023-06-08 Release date: 2024-06-26 Last modified: 2025-01-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer. J.Med.Chem., 67, 2024
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2023-06-08
