RNA-seq data from the trachea epithelial cells of two inbred chicken lines at three time points after challenge with lentogenic Newcastle disease virus. RNA-seq data from the trachea epithelial cells of two inbred chicken lines at three time points after challenge with lentogenic Newcastle disease virus

This study aimed to characterize differential responses between the relatively resistant (Fayoumi) and susceptible (Leghorn) chicken lines when challenged with a high titered lentogenic Newcastle Disease Virus (NDV) strain via the eyes and nostrils at three weeks of age. The trachea epithelial cells were collected from challenged and non-challenged birds from each line at 2, 6, and 10 days-post-infection (dpi). High quality RNA was isolated, used for cDNA library construction, and sequenced on the HiSeq2500.