Corneal Laser Procedure for safety and efficacy in vision improvement

Purpose: To determine the safety and efficacy of corneal photovitrification (CPV), a corneal laser procedure, for vision improvement in patients with neovascular age-related macular degeneration (nAMD) and other retinal disorders involving central vision loss.
Design: Retrospective observational cohort study.
Methods: In this retrospective observational case series, 72 eyes of 54 patients received a single CPV treatment. Examinations included pre- and post-treatment (post-Tx) best-corrected distance visual acuity (BCDVA) and pre-Tx potential visual acuity (PVA).
Results: Safety - No clinically significant complications or serious adverse events were observed. Efficacy – Mean BCDVA improved significantly from 20/303 (1.18 logMAR, 26 letters) at baseline to 20/208 (1.02 logMAR, 34 letters) at 1m post-Tx (p = 0.000001) for a cohort of 57 eyes, improving to 20/198 (1.00 logMAR, 35 letters; 11.0 mean letters gained) at 12m (p = 0.0009) for a cohort of 29 eyes. Screening – Mean pre-Tx PVA gai...