Fig 7: Thalamocortical fEPSP amplitude measured before and after prolonged periods of sleep or wake

(A) Hypnograms showing an example of a wake (left) and sleep (right) dense epoch, with flanking periods of the opposite state. Grey rectangles indicate when measurements were taken for comparison. (B) Example fEPSP waveforms before and after a wake (left) or sleep (right) dense epoch. (C) Normalized change in fEPSP amplitude after wake or sleep (wake change, p>0.9; sleep change, p>0.9; Wilcoxon signed-rank test). (D) Correlative plot of duration of wake dense epoch against normalized change in fEPSP amplitude. Black line = linear fit; R2 value and p value included on plot. Inset in top right is an expansion of plot between 0 and 3.5 hours. (E) Same as (D) but for sleep dense. N = 39 wake dense epochs, 55 sleep dense epochs, 4 animals.