Crystal structure of JAK3 in complex with Delgocitinib
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of JAK3 in complex with Delgocitinib Descriptor: 3-[(3S,4R)-3-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile, Tyrosine-protein kinase JAK3 Authors: Doi, S, Otira, T, Kikuwaka, M, Nomura, A, Noji, S, Adachi, T. Deposit date: 2020-05-13 Release date: 2020-06-24 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders. J.Med.Chem., 63, 2020
创建时间：
2020-05-13
