Effect of Arg2 deletion on murine liver gene expression profiles in aging mice

We demonstrate the long term physiologic consequences of hepatocyte-specific Arg2 deficiency on murine liver gene expression in chow-fed mice at 22-month of age by high-throughput RNA sequencing Overall design: Examination of transcriptome changes in hepatocyte-specific Arg2 deficient murine livers compared to their Arg2 floxed WT littermates at 22-month-old.