Investigation of a S. argenteus strain involved in a chronic prosthetic-joint infeciton

Staphylococcus argenteus is an emerging species responsible for infections comparable to those induced by Staphylococcus aureus. It has been involved in few chronic or persistent infections so far. In this study we described a case of a persistent prosthetic-joint infection (PJI) affecting a young woman. We investigated in vitro the virulence traits of the isolated strain (bone cell invasion, biofilm formation, induction of inflammation) and analyzed its genome, in comparison with two strains of S. aureus and two other S. argenteus isolates.