PhageWA/PHROGs HMM Annotation Database

The PhageWA/PHROGs HMM Annotation Database is a custom protein annotation database developed for the functional annotation of bacteriophage genomes. Version 1.0 combines hidden Markov model (HMM) profiles from the PHROGs v4 database with additional profiles derived from bacteriophages in the PhageWA collection. The combined database expands the available reference profiles for identifying and annotating proteins encoded by bacteriophage genomes. This Zenodo record contains version 1.0 of the database. The Phlex Developer Manual (SM-002) describes the process used to build, update, and index the database. This database is intended for research and software-testing purposes. Functional annotations generated using the database should be reviewed and interpreted alongside additional biological evidence.