Expression of 97 surface markers and 462 mRNAs in 49057 cells from healthy young and healthy old bone marrow

Name: Expression of 97 surface markers and 462 mRNAs in 49057 cells from healthy young and healthy old bone marrow
Creator: Triana, Sergio; Velten, Lars; Haas, Simon; Paulsen, Malte; Vonficht, Dominik; Jopp-Saile, Lea
Published: 2021-06-15 00:00:00
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Figshare2021-06-15 更新2026-04-08 收录

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https://figshare.com/articles/dataset/Expression_of_97_surface_markers_and_462_mRNAs_in_70017_cells_from_healthy_young_healthy_old_and_leukemic_human_bone_marrow/13397651/2

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Seurat v3 object ASSAYS:AB: Antibody expression dataRNA: mRNA expression dataBOTH: mRNA and Antibody expression data, concatenatedintegrated: Antibody and mRNA expression matrices were concatenated and data was integrated across patients using scanorama DIMENSIONALITY REDUCTIONMOFAUMAP: UMAP performed on MOFA dimensions. Display used in the manuscript. Set reduction="MOFAUMAP"in most cases! ProjectedMOFA: Multi-OMICS factor analysis to integrate AB and RNA data. MOFA was run on scanorama-integrated data and served as input for clustering and further dimensionality reduction.MOFATSNE: UMAP performed on MOFA dimensions. METADATABatch: Source individual (BM1-3, Aged1-3).class: Type of individual (healthy young, healthy old). Change log: Compared to the previous version of this file, the 3 AML patients were removed. A new object with 15 AML patients has been created: https://doi.org/10.6084/m9.figshare.14780127.v1

提供机构：

Triana, Sergio; Velten, Lars; Haas, Simon; Paulsen, Malte; Vonficht, Dominik; Jopp-Saile, Lea

创建时间：

2021-06-15