PRM based validation of cisplatin resistant associated metabolites in TNBC
收藏DataCite Commons2025-11-01 更新2026-05-07 收录
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资源简介：
The study explores molecular drivers of cisplatin resistance in triple-negative breast cancer (TNBC) through mass spectrometry analysis. It identifies key metabolic pathways and altered metabolites, including sphingolipid and glycerophospholipid metabolism, aminoacyl t-RNA biosynthesis, and specific metabolites like N8-acetylspermidine and pantothenic acid. These findings shed light on TNBC aggressiveness and may inform strategies to overcome treatment limitations.
提供机构：
Panorama Public
创建时间：
2024-04-06
