Characterisation of selected hits.

The controls are marked in italics. The subcellular localisation of the candidates marked with # was further analysed (in Table 3).
tER-Golgi phenotype: MG, More and smaller tER-Golgi units. The phenotype ranges from ++++ (strongest) to + (marginal). See also Table S2.
Cell proliferation: Double or single arrows indicate statistically significant (p<0.05) or a tendency (0.05Figure 4A.
Cell cycle: Conditions resulting in a G1 or S/G2/M block are marked by double or single arrows depending on statistical significance.
‡indicates conditions with increased sub-G1 cell population. See also Figure 4B.
Average cell diameter (normalized to mock-treated cells): Values marked in bold indicate hits with p<0.05 and asterisks indicate hits with 0.05
Lipid droplets: Double or single arrows indicate statistically significant (p<0.05) or a tendency (0.05Figure 5B–C.
TOR activation: “no” indicates the protein depletions with no increase in phospho-S6K. See also Figure 5D.