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A BDNF-TrkB autocrine loop enhances senescent cell viability [scRNA-seq]

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE202950
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We used single cell RNA sequencing (scRNA-seq) to investigate the RNA expression correlation between BDNF and STAT3-associated targets in etoposide-treated human fibroblast cell populations. Proliferating human fibroblasts (WI-38 cells) were treated with etoposide to trigger senescent-like phenotypes. Cells were trypsinized, washed and then subjected to scRNA-seq experiment.
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2022-10-28
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