Pairs of alternative polyA site analyzes in this study.

For E13.5 or E18.5, a pair of alternative polyA sites per gene was selected (see Methods for details). Genomic features, raw read counts, and log2 FCs for each KO versus WT (KO/WT) comparison and E18.5 versus E13.5 using the proximal polyA site as reference are provided. Enhanced/Repressed indicates a given polyA pair is significantly differentially regulated in the KO and the direction refers to the proximal polyA, e.g., an enhanced pair means the proximal site is up-regulated in the KO. KO_Up/KO_Down indicates that the proximal site is up/down-regulated in the KO, but not reaching statistical significance. FC, fold change; KO, knockout; WT, wild-type. (XLSX)