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Next generation sequencing of chicken otocyst with pharmacologicaly induced loss-of-Wnt signalling

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE161638
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资源简介:
Bulk RNA-sequencing of individual E2.5 chicken otocyst incubated in media enriched with Wnt signalling inhibitor IWR-1 or control condition (DMSO) for 24h. Transcripts abundance was mapped to a chicken reference genome using Kallisto package and differentially expressed genes were identify using Sleuth package (genes with p-value < 0.05 were considered as significant). Biological Function enrichment analysis (Toppgene online tool) showed that many of these genes were associated with neurogenesis. Identification of genes deregulated in E3 otic explants treated with IRW-1 or DMSO for 24h
创建时间:
2021-04-03
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