BIOGRID CURATED DATA FOR PFD1 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for PFD1 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Subunit of heterohexameric prefoldin; prefoldin binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation

Protein-Protein, Genetic, and Chemical Interactions for PFD1 (酿酒酵母(S288c))，由BioGRID（https://thebiogrid.org）编纂；定义：异六元前折叠素亚基；前折叠素结合细胞质伴侣蛋白，并将靶蛋白转移至其上；参与肌动蛋白以及α-和γ-微管蛋白的生物发生；前折叠素复合物亦定位于细胞核中活跃转录基因的染色质，并促进转录延伸。