The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 11b/j

The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 11b/j Descriptor: 3-cyclohexyl-1,19-dimethoxy-11,16-dioxa-19lambda4-polona-1,13-diaza-2lambda5-polonapentacyclo[16.4.0.04,9.013,19.020,25]docosane-2,12-dione, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Meyners, C, Buffa, V, Walz, C, Hausch, F. Deposit date: 2024-09-09 Release date: 2025-01-15 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Conformational Plasticity and Binding Affinity Enhancement Controlled by Linker Derivatization in Macrocycles. Angew.Chem.Int.Ed.Engl., 64, 2025