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Treg cell gene expression signature in B16 melanoma. Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA344445
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Gene expression signature of Treg cells in B16 melanoma was measured and compared to B16-infiltrating CD4+ Tconv cells and CD8+ T cells as well as splenic Treg cells, CD4+ Tconv cells and CD8+ T cells. Overall design: We isolated regulatory and conventional CD4+ T cells as well as CD8+ T cells from B16 melanoma and spleen of mice. Cells were isolated, pooled and target cells were purified by FACS. RNA was extracted and gene expression measured.
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2016-09-26
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