The gene signature from the microarray dataset using SamR analysis.

The list of identifiers and their associated genes extracted from the microarray using SamR analysis and put to the sscMap. 18 out these 23 gene identifiers are also identified as differentially expressed genes (DEGs) by the DESeq analysis on the NGS dataset (Table S1). NA indicates that the corresponding gene was not returned as DEG by DESeq and hence is not found in Table S1. Expression fold change is defined as ratio (stimulated/unstimulated). Note that Dseq reported 0 expression for this gene in the unstimulated state, hence ratio(stimulated/unstimulated) and logratio are not defined. Table S5 also contains the signed ranks of these 23 probesetIDs in the 6 instances of reference profiles for cotinine.