Examples of metabolite patterns in tuberculosis patients (TBactive), healthy uninfected (TST–) and latently infected (TST+) individuals.

(A) Changes in relative abundance of three exemplary small metabolites: fibrinopeptide A, inosine and kynurenine. Red line indicates sample mean, blue line indicates sample median. Stars indicate significant differences between profiles (result from t-test corrected for multiple testing; *, p–; green circles, TST+; red triangles, TBactive. Spearman correlation coefficients (rho) and corresponding p-values are given.