List of the specific sequences of Oct4, Klf4 and Sox2.
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List of the specific sequences of Oct4, Klf4 and Sox2.
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2015-12-02
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Reprogramming of mouse somatic cells into pluripotent stem cells using a combination of small molecules
Somatic cells can be reprogrammed to generate induced pluripotent stem cells (iPSCs) by overexpression of four transcription factors, Oct4, Klf4, Sox2, and c-Myc. Bmi1 is responsible for conversion o
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Analysis of Differential Proteomes of Induced Pluripotent Stem Cells by Protein-Based Reprogramming of Fibroblasts
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The trophectoderm acts as a niche for the inner cell mass through IL-6 signaling [reprogramming_embryo]. The trophectoderm acts as a niche for the inner cell mass through IL-6 signaling [reprogramming_embryo]
IL-6 has been shown to be required for somatic cell reprogramming into induced pluripotent stem cells (iPSCs). However, how the cytokine is regulated and if it plays a role during embryo development r
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Epigenetic and transcriptional aberrations in human pluripotent stem cells reflect differences in reprogramming mechanisms [SNP array]
Human pluripotent stem cells hold great potential for regenerative medicine, but available cell types have important limitations. While embryonic stem cells derived from fertilized embryos (IVF-ESCs)
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