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Inhibition of AQP8 mitigates intestinal flora disruption in CKD mice

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP492508
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Previous studies have shown that there is a close connection between constipation symptoms and gut flora disorders.In our study, knockdown of AQP8 could alleviate constipation in CKD mice by improving intestinal water-liquid transport and making feces soft and lubricated.Therefore, we investigated the effects of inhibiting AQP8 expression on the gut microbiota of CKD mice using 16S ribosomal RNA (rRNA) sequencing.
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2025-03-28
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