BIOGRID CURATED DATA FOR UFD4 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for UFD4 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Ubiquitin-protein ligase (E3); interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins; relative distribution to the nucleus increases upon DNA replication stress

由BioGRID（https://thebiogrid.org）精心编纂的UFD4（酿酒酵母S288c）蛋白质-蛋白质、遗传和化学相互作用数据集；定义：泛素蛋白连接酶（E3）；与Rpt4p和Rpt6p相互作用，后者为26S蛋白酶体19S颗粒的两个亚基；作为细胞质中的E3，参与泛素融合蛋白的降解；在DNA复制压力下，相对于细胞核的分布比例增加。