Inhibition of ABCC4-mediated 3-series prostanoids transport.
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Membrane vesicles (25 µg) from HEK293 or HEK293/4.63 cells were incubated with PGE3 (1 µM), PGF3α (2.5 µM), or TXB3 (2.5 µM) at 37°C. Rates of ATP-dependent transport were calculated by subtracting the uptake in the presence of AMP from that in the presence of ATP. Transport is expressed as percent of uptake in the absence of inhibitor. Each value represents the mean ± S.E. (n = 3).
*; p<0.05.
**; p<0.01.
Inhibition of ABCC4-mediated 3-series prostanoids transport.
创建时间:
2014-10-02



