Developing a Raman spectroscopy-based tool to stratify patient response to pre-operative radiotherapy in rectal cancer - dataset

Rectal cancer patients frequently receive pre-operative radiotherapy (RT), prior to surgical resection. However, colorectal cancer is heterogeneous and the degree of tumour response to pre operative RT is highly variable. There are currently no clinically approved methods of predicting response to RT, and a significant proportion of patients will show no clinical benefit, despite enduring the side-effects. This dataset contains the raw and pre-processed Raman spectra taken from the biopsy specimens of 20 rectal cancer patients who showed a varying degree of tumour response to RT. This data was used in the multivariate analysis described in the associated paper to predict patient response to pre-operative RT.