scRNA-seq data of spleen immune cells from Vehicle- and Glutoborin-treated mice

To determine whether Glutoborin exerts its immunomodulatory effects by disrupting interactions between MZMs and MZBs, we performed scRNA-seq to analyze the immune microenvironment of spleens from Pb-infected mice treated with Vehicle or Glutoborin. Overall design: Mice were intraperitoneally injected with 1 × 104 iRBCs, and on days 2 and 4 post-infection Vehicle and Glutoborin were administered. On day 5 post-infection spleens from both group were collected to isolate lymphocytes. CD45+ cells were then sorted by flow cytometry for subsequent single-cell sequencing analysis.