DMPs identified in disease vs. controls classified by probe type (Island, Shelf, and Shore).

Hypomethylated DMPs are overrepresented in CpG islands when comparing FTD vs. controls, and both hyper- and hypomethylated DMPs are overrepresented in CpG islands in PSP vs. controls. Chi-square test was performed within hyper and hypo-methylated DMPs (p-value column) or across all DMPs (overall p-value column) by considering the proportion of all probes on the chip as population frequencies.