GATA-6 and NFkB Repress Caveolins Transcription in Bladder Smooth Muscle Hypertrophy
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE107427
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资源简介：
Microarray analysis of bladder RNA revealed down-regulation of CAV1, CAV2 and CAV3 gene transcription in both mice with obstruction-induced BSM hypertrophy, and in men with benign prostatic hyperplasia Knockout of NF-κB subunits or shRNA-mediated knockdown of GATA-6 in BSM increased CAV1, CAV2 and CAV3 transcription and promoter activity. In this study, we performed a comprehensive analysis of genes regulation under conditions relevant to BSM hypertrophy and obstructive bladder disease.
创建时间：
2019-03-21
