Figure S1 - In Silico, In Vitro and In Vivo Analysis of Binding Affinity between N and C-Domains of Clostridium perfringens Alpha Toxin

Superposition of Cp-PLC (PDB ID: 1CA1) and modelled Cp-PLC N and C-domain complex with N-domain in ribbon format and C-domain in stick format. Cp-PLC N and C-domain residues are colored green and cyan, respectively and N and C-domains of the complex are colored pink and brown, respectively. The shift in orientation of C-domain is showed by arrow. (PPTX)