human gut metagenome Metagenome

In a previously published double-blind, placebo-controlled study, we showed that probiotics intake exerted a positive effect on sleep quality and a general improvement across time in different aspects of the profile of mood state, like sad mood, anger, and fatigue in 33 healthy individuals.The present study a metabarcoding analysis of the fecal microbiota was applied to determine the microbial composition at the baseline in the same cohort of healthy adults and to determine the effects of the probiotic and placebo consumptions during and after the administration.