The top 25 genes up-regulated or down-regulated by PR/8 infection in human AM at 4 hpi.

Human AM from 3 non-smoking donors were isolated, cultured, and infected by PR/8 virus at a MOI of 0.5. The gene profiling of infected and non-infected cells at 4 hpi from each donor was examined by microarray experiments using Affymetrix HG-U133 Plus 2.0 chips (Affymetrix, Santa Clara, CA). The filtered gene list was generated as described in the Section of Methods. The data show the top 25 genes up-regulated or down-regulated altered by viral infection. *indicates similar results from multiple probes.