Characteristics of included studies and reported dementia risk prediction models.

* Genetic Risk Score includes the following: CLU, PICALM, BIN1, CR1, ABCA7, MS4A6A, MS4A4E, CD2AP, EPHA1, and CD33.Abbreviations: 4-IADL, Four instrumental activities of daily living; AD, Alzheimer disease; ADAS, Alzheimer's Disease Assessment Scale; ADAS-Cog, Alzheimer's Disease Assessment Scale—cognitive subscale; ANU-ADRi, Australian National University AD Risk Index; APOE, apolipoprotein E; AUC, Area Under the Receiver Operating Characteristic Curve; BVRT, Benton Visual Retention Test; BMI, Body Mass Index; CAIDE, Cardiovascular Risk Factors, Aging and Dementia Study; Cal, calibration; CAMCOG Cambridge Cognitive Examination; CDT, Clock Drawing Test; CERAD, Consortium to Establish a Registry for ADDSM, Diagnostic and Statistical Manual of Mental Disorders; DSST, Digit Symbol Substitution Test; Ex val, external validation; FCSRT-FR, Free recall score from the Free and Cued Selective Reminding Test; FCSRT-TR, Total recall score from the Free and Cued Selective Reminding Test; FTD, Frontotemporal Dementia; GDS, Geriatric Depression Scale; HEL, High Education Level; HI, Head Injury; IAD, Instrumental Activities of Daily Living Scale; ICD-9, International Classification of Diseases, Ninth Revision; IST, Isaacs Set Test; IDSR, Intra-categorical Delayed Selective Reminding test; LEL, Low educational Level, LOAD, Late-onset AD; LM-IR, Logical Memory I immediate recall; MCI, Mild Cognitive Impairment; MMSE, Mini Mental State Examination; NINCDS–ADRDA, Alzheimer's Criteria National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association; NINCDS–AIREN, Vascular Dementia Criteria National Institute of Neurological Disorders and Stroke and Association Internationale pour la Recherché et l'Enseignement en Neurosciences; NOS, not otherwise specified; RAVLT, Rey Auditory–Verbal Learning Test; SMI, Subjective Memory Impairment; Sn, Sensitivity; Sp, Specificity; VaD, Vascular Dementia; VADAS, Vascular Dementia Assessment Scale; WAIS-R, The Wechsler Adult Intelligence Scale-Revised; WMS, Wechsler Memory Scale.Characteristics of included studies and reported dementia risk prediction models.